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The gain-of-function allele bamA(E470K) bypasses the essential requirement for BamD in β-barrel outer membrane protein assembly

The outer membrane (OM) of gram-negative bacteria confers innate resistance to toxins and antibiotics. Integral β-barrel outer membrane proteins (OMPs) function to establish and maintain the selective permeability of the OM. OMPs are assembled into the OM by the β-barrel assembly machine (BAM), whic...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Hart, Elizabeth M., Gupta, Meera, Wühr, Martin, Silhavy, Thomas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414184/
https://ncbi.nlm.nih.gov/pubmed/32675245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007696117
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