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Phosphorylation of the Arginine-Rich C-Terminal Domains of the Hepatitis B Virus (HBV) Core Protein as a Fine Regulator of the Interaction between HBc and Nucleic Acid

The morphogenesis of Hepatitis B Virus (HBV) viral particles is nucleated by the oligomerization of HBc protein molecules, resulting in the formation of an icosahedral capsid shell containing the replication-competent nucleoprotein complex made of the viral polymerase and the pre-genomic RNA (pgRNA)...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: de Rocquigny, Hugues, Rat, Virgile, Pastor, Florentin, Darlix, Jean Luc, Hourioux, Christophe, Roingeard, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7412469/
https://ncbi.nlm.nih.gov/pubmed/32650547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12070738
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