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An in vitro model for hypertrophic adipocytes: Time‐dependent adipocyte proteome and secretome changes under high glucose and high insulin conditions

Obesity is the consequence of a positive energy balance and characterized by enlargement of the adipose tissue, which in part is due to hyperplasia and hypertrophy of the adipocytes. Not much is known about the transition of normal mature adipocytes to the hypertrophic state, which in vivo is very h...

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Bibliographic Details
Published in:J Cell Mol Med
Main Authors: Qiao, Qi, Bouwman, Freek G., Renes, Johan, Mariman, Edwin C. M.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7412416/
https://ncbi.nlm.nih.gov/pubmed/32618419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15497
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