Molecular Features and Metal Ions That Influence 10-23 DNAzyme Activity

Deoxyribozymes (DNAzymes) with RNA hydrolysis activity have a tremendous potential as gene suppression agents for therapeutic applications. The most extensively studied representative is the 10-23 DNAzyme consisting of a catalytic loop and two substrate binding arms that can be designed to bind and...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Rosenbach, Hannah, Victor, Julian, Etzkorn, Manuel, Steger, Gerhard, Riesner, Detlev, Span, Ingrid
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7412337/
https://ncbi.nlm.nih.gov/pubmed/32646019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25133100
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