MAVS Genetic Variation Is Associated with Decreased HIV-1 Replication In Vitro and Reduced CD4(+) T Cell Infection in HIV-1-Infected Individuals

The mitochondrial antiviral protein MAVS is a key player in the induction of antiviral responses; however, human immunodeficiency virus 1 (HIV-1) is able to suppress these responses. Two linked single nucleotide polymorphisms (SNPs) in the MAVS gene render MAVS insensitive to HIV-1-dependent suppres...

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Publicado no:Viruses
Main Authors: Stunnenberg, Melissa, van Pul, Lisa, Sprokholt, Joris K., van Dort, Karel A., Gringhuis, Sonja I., Geijtenbeek, Teunis B. H., Kootstra, Neeltje A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7412276/
https://ncbi.nlm.nih.gov/pubmed/32708557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12070764
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