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HEPCIDIN, AN IRON REGULATORY HORMONE OF INNATE IMMUNITY, IS DIFFERENTIALLY EXPRESSED IN PREMATURE FETUSES WITH EARLY-ONSET NEONATAL SEPSIS

OBJECTIVE: Hepcidin, a mediator of innate immunity, binds the iron exporter ferroportin, leading to functional hypoferremia through intracellular iron sequestration. We explored hepcidin-ferroportin interactions in neonates clinically diagnosed with early-onset neonatal sepsis (EONS). STUDY DESIGN:...

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Detalhes bibliográficos
Publicado no:Am J Perinatol
Main Authors: Tabbah, Sammy M., Buhimschi, Catalin S., Rodewald-Millen, Katherine, Pierson, Christopher R., Bhandari, Vineet, Samuels, Philip, Buhimschi, Irina A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7412256/
https://ncbi.nlm.nih.gov/pubmed/29532452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0038-1626711
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