Human Endogenous Retrovirus K in Cancer: A Potential Biomarker and Immunotherapeutic Target

In diseases where epigenetic mechanisms are changed, such as cancer, many genes show altered gene expression and inhibited genes become activated. Human endogenous retrovirus type K (HERV-K) expression is usually inhibited in normal cells from healthy adults. In tumor cells, however, HERV-K mRNA exp...

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Bibliographic Details
Published in:Viruses
Main Authors: Curty, Gislaine, Marston, Jez L., de Mulder Rougvie, Miguel, Leal, Fabio E., Nixon, Douglas F., Soares, Marcelo A.
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7412025/
https://ncbi.nlm.nih.gov/pubmed/32640516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12070726
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