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New Paracyclophanylthiazoles with Anti-Leukemia Activity: Design, Synthesis, Molecular Docking, and Mechanistic Studies

A new series of methyl 2-(2-(4′-[2.2]paracyclophanyl)-hydrazinylidene)-3-substituted-4-oxothiazolidin-5-ylidene)acetates 3a–f were synthesized from the reaction of paracyclophanyl-acylthiosemicarbazides 2a–f with dimethyl acetylenedicarboxylate. Based upon nuclear magnetic resonance (NMR), infrared...

詳細記述

保存先:
書誌詳細
出版年:Molecules
主要な著者: Aly, Ashraf A, Bräse, Stefan, Hassan, Alaa A., Mohamed, Nasr K., Abd El-Haleem, Lamiaa E., Nieger, Martin, Morsy, Nesrin M., Abdelhafez, Elshimaa M. N.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411887/
https://ncbi.nlm.nih.gov/pubmed/32645912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25133089
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