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Nano Ellagic Acid Counteracts Cisplatin-Induced Upregulation in OAT1 and OAT3: A Possible Nephroprotection Mechanism

Cisplatin is an anticancer drug commonly used for solid tumors. However, it causes nephrotoxicity. OAT1 and OAT3 are organic anion transporters known to contribute to the uptake of cisplatin into renal tubular cells. The present study was designed to examine the protective role of ellagic acid nanof...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Neamatallah, Thikryat, El-Shitany, Nagla, Abbas, Aymn, Eid, Basma G., Harakeh, Steve, Ali, Soad, Mousa, Shaker
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411712/
https://ncbi.nlm.nih.gov/pubmed/32630784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25133031
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