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Inside Out Integrin Activation Mediated by PIEZO1 Signaling in Erythroblasts
The non-selective mechanosensitive ion channel PIEZO1 controls erythrocyte volume homeostasis. Different missense gain-of-function mutations in PIEZO1 gene have been identified that cause Hereditary Xerocytosis (HX), a rare autosomal dominant haemolytic anemia. PIEZO1 expression is not limited to er...
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| Publicado no: | Front Physiol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7411472/ https://ncbi.nlm.nih.gov/pubmed/32848880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00958 |
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