ACY-1215, a HDAC6 inhibitor, decreases the dexamethasone-induced suppression of osteogenesis in MC3T3-E1 cells

Glucocorticoid-induced osteoporosis is the commonest form of drug-induced osteoporosis. Histone deacetylase 6 (HDAC6) is involved in the differentiation from mesenchymal stem cells to osteoblasts. However, the role of ricolinostat (ACY-1215, HDAC6 inhibitor) in the dexamethasone (Dex)-induced prolif...

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Publicado no:Mol Med Rep
Main Authors: Wang, Na, Wang, Hua, Chen, Jianming, Wang, Fubin, Wang, Shuaiyi, Zhou, Qiang, Ying, Jichong, Huang, Shanzhao, Wang, Pu, Yuan, Fangfang
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411391/
https://ncbi.nlm.nih.gov/pubmed/32705192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11319
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