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MicroRNA-375 prevents TGF-β-dependent transdifferentiation of lung fibroblasts via the MAP2K6/P38 pathway

Transdifferentiation of lung fibroblasts to myofibroblasts is a crucial pathophysiological process in pulmonary fibrosis. MicroRNA-375 (miR-375) was initially identified as a tumor-suppressive factor, and its expression was negatively associated with the severity of lung cancer; however, its role an...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Zhang, Xinghua, Chen, Qian, Song, Hengya, Jiang, Wanli, Xie, Songping, Huang, Jie, Kang, Ganjun
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411355/
https://ncbi.nlm.nih.gov/pubmed/32582987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11261
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