Peroxiredoxin I deficiency increases pancreatic β-cell apoptosis after streptozotocin stimulation via the AKT/GSK3β signaling pathway

Apoptosis of pancreatic β-cells is involved in the pathogenesis of type I and II diabetes. Peroxiredoxin I (Prx I) serves an important role in regulating cellular apoptosis; however, the role of Prx I in pancreatic β-cell apoptosis is not completely understood. In the present study, the role of pero...

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Udgivet i:Mol Med Rep
Main Authors: Jin, Mei-Hua, Shen, Gui-Nan, Jin, Ying-Hua, Sun, Hu-Nan, Zhen, Xing, Zhang, Yong-Qing, Lee, Dong-Seok, Cui, Yu-Dong, Yu, Li-Yun, Kim, Ji-Su, Kwon, Taeho, Han, Ying-Hao
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2020
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411341/
https://ncbi.nlm.nih.gov/pubmed/32705184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11279
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