Gene design, optimization of protein expression and preliminary evaluation of a new chimeric protein for the serological diagnosis of both human and canine visceral leishmaniasis

BACKGROUND: Visceral leishmaniasis (VL) is a major neglected disease, potentially fatal, whose control is still impaired by inefficient and/or expensive treatment and diagnostic methods. The most promising approach for VL diagnosis uses serological assays with recombinant proteins, since they are mo...

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Publicat a:PLoS Negl Trop Dis
Autors principals: Santos, Wagner J. T., Tavares, Diego H. C., Castro Neto, Artur L., Nascimento, Marília B., Dhalia, Rafael, Albuquerque, Alessandra L., Costa, Carlos H. N., Magalhães, Franklin B., Rezende, Antônio M., de Melo Neto, Osvaldo P.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410341/
https://ncbi.nlm.nih.gov/pubmed/32716931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008488
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