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Gut microbiome communication with bone marrow regulates susceptibility to amebiasis

The microbiome provides resistance to infection. However, the underlying mechanisms are poorly understood. We demonstrate that colonization with the intestinal bacterium Clostridium scindens protects from Entamoeba histolytica colitis via innate immunity. Introduction of C. scindens into the gut mic...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Burgess, Stacey L., Leslie, Jhansi L., Uddin, Jashim, Oakland, David N., Gilchrist, Carol, Moreau, G. Brett, Watanabe, Koji, Saleh, Mahmoud, Simpson, Morgan, Thompson, Brandon A., Auble, David T., Turner, Stephen D., Giallourou, Natasa, Swann, Jonathan, Pu, Zhen, Ma, Jennie Z., Haque, Rashidul, Petri, William A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410058/
https://ncbi.nlm.nih.gov/pubmed/32369444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133605
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