Maternal diesel particle exposure promotes offspring asthma through NK cell–derived granzyme B

Mothers living near high-traffic roads before or during pregnancy are more likely to have children with asthma. Mechanisms are unknown. Using a mouse model, here we showed that maternal exposure to diesel exhaust particles (DEP) predisposed offspring to allergic airway disease (AAD, murine counterpa...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Qian, Qian, Chowdhury, Bidisha Paul, Sun, Zehua, Lenberg, Jerica, Alam, Rafeul, Vivier, Eric, Gorska, Magdalena M.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410053/
https://ncbi.nlm.nih.gov/pubmed/32407293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130324
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