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Anti-complement C5 therapy with eculizumab in three cases of critical COVID-19

Respiratory failure and acute kidney injury (AKI) are associated with high mortality in SARS-CoV-2-associated Coronavirus disease 2019 (COVID-19). These manifestations are linked to a hypercoaguable, pro-inflammatory state with persistent, systemic complement activation. Three critical COVID-19 pati...

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Detalhes bibliográficos
Publicado no:Clin Immunol
Main Authors: Laurence, Jeffrey, Mulvey, J. Justin, Seshadri, Madhav, Racanelli, Alexandra, Harp, Joanna, Schenck, Edward J., Zappetti, Dana, Horn, Evelyn M., Magro, Cynthia M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410014/
https://ncbi.nlm.nih.gov/pubmed/32771488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2020.108555
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