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Predicting novel drugs for SARS-CoV-2 using machine learning from a >10 million chemical space

There is an urgent need for the identification of effective therapeutics for COVID-19 and we have developed a machine learning drug discovery pipeline to identify several drug candidates. First, we collect assay data for 65 target human proteins known to interact with the SARS-CoV-2 proteins, includ...

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Bibliografiske detaljer
Udgivet i:Heliyon
Main Authors: Kowalewski, Joel, Ray, Anandasankar
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409807/
https://ncbi.nlm.nih.gov/pubmed/32802980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2020.e04639
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