Standardized ethanol extract of Tinospora crispa upregulates pro-inflammatory mediators release in LPS-primed U937 human macrophages through stimulation of MAPK, NF-κB and PI3K-Akt signaling networks

BACKGROUND: Immunomodulatory effects of Tinospora crispa have been investigated due to its traditional use to treat several inflammatory disorders associated to the immune system. The present study reports the underlying mechanisms involved in the stimulation of 80% ethanol extract of T. crispa stem...

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Bibliographic Details
Published in:BMC Complement Med Ther
Main Authors: Haque, Md. Areeful, Jantan, Ibrahim, Harikrishnan, Hemavathy, Ahmad, Waqas
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409646/
https://ncbi.nlm.nih.gov/pubmed/32762741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-020-03039-7
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