Hypoxia alleviates dexamethasone-induced inhibition of angiogenesis in cocultures of HUVECs and rBMSCs via HIF-1α

BACKGROUND AND AIM: Inadequate vascularization is a challenge in bone tissue engineering because internal cells are prone to necrosis due to a lack of nutrient supply. Rat bone marrow-derived mesenchymal stem cells (rBMSCs) and human umbilical vein endothelial cells (HUVECs) were cocultured to const...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Chai, Miaomiao, Gu, Ce, Shen, Qihua, Liu, Jiaxing, Zhou, Yi, Jin, Ziyang, Xiong, Wanli, Zhou, Yan, Tan, Wensong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409505/
https://ncbi.nlm.nih.gov/pubmed/32762747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01853-x
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