Molecular characterization of Plasmodium falciparum DNA-3-methyladenine glycosylase

BACKGROUND: The emergence of artemisinin-resistant malaria parasites highlights the need for novel drugs and their targets. Alkylation of purine bases can hinder DNA replication and if unresolved would eventually result in cell death. DNA-3-methyladenine glycosylase (MAG) is responsible for the repa...

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Udgivet i:Malar J
Main Authors: Pinthong, Nattapon, Limudomporn, Paviga, Vasuvat, Jitlada, Adisakwattana, Poom, Rattaprasert, Pongruj, Chavalitshewinkoon-Petmitr, Porntip
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409487/
https://ncbi.nlm.nih.gov/pubmed/32762689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-020-03355-w
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