Natural Killer Cell Activation Receptor NKp30 Oligomerization Depends on Its N-Glycosylation

NKp30 is one of the main human natural killer (NK) cell activating receptors used in directed immunotherapy. The oligomerization of the NKp30 ligand binding domain depends on the length of the C-terminal stalk region, but our structural knowledge of NKp30 oligomerization and its role in signal trans...

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Pubblicato in:Cancers (Basel)
Autori principali: Skořepa, Ondřej, Pazicky, Samuel, Kalousková, Barbora, Bláha, Jan, Abreu, Celeste, Ječmen, Tomáš, Rosůlek, Michal, Fish, Alexander, Sedivy, Arthur, Harlos, Karl, Dohnálek, Jan, Skálová, Tereza, Vaněk, Ondřej
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409301/
https://ncbi.nlm.nih.gov/pubmed/32708305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071998
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