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Humanized Mice Are Precious Tools for Preclinical Evaluation of CAR T and CAR NK Cell Therapies

Chimeric antigen receptor (CAR) T-cell therapy represents a revolutionary treatment for hematological malignancies. However, improvements in CAR T-cell therapies are urgently needed since CAR T cell application is associated with toxicities, exhaustion, immune suppression, lack of long-term persiste...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Mhaidly, Rana, Verhoeyen, Els
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409195/
https://ncbi.nlm.nih.gov/pubmed/32679920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071915
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