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Rapid and Sensitive Quantification of Osimertinib in Human Plasma Using a Fully Validated MALDI–IM–MS/MS Assay

The third-generation tyrosine kinase inhibitor (TKI), osimertinib, has revolutionized the treatment of patients with non-small cell lung carcinoma with epidermal growth factor receptor (EGFR)-activating mutation, and resistant to first- and second-generation TKIs. Osimertinib is now also proposed as...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Fresnais, Margaux, Roth, André, Foerster, Kathrin I., Jäger, Dirk, Pfister, Stefan M., Haefeli, Walter E., Burhenne, Jürgen, Longuespée, Rémi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409122/
https://ncbi.nlm.nih.gov/pubmed/32674434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071897
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