Intraocular Distribution and Kinetics of Intravitreally Injected Antibodies and Nanoparticles in Rabbit Eyes

PURPOSE: To investigate the intraocular distribution and kinetics of antibodies and nanoparticles in the experimental model. METHODS: Antibodies (whole IgG 149kDa, antigen-binding fragments 48.39 kDa) and four kinds of nondegradable nanoparticles (25, 50, 200, and 250 nm) were intravitreally injecte...

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Published in:Transl Vis Sci Technol
Main Authors: Kim, Hyeong Min, Ha, Seungmin, Hong, Hye Kyoung, Hwang, Yoonha, Kim, Pilhan, Yang, Eunsol, Chung, Jae Yong, Park, Sunyoung, Park, Young Joo, Park, Kyu Hyung, Kim, Hyuncheol, Woo, Se Joon
Format: Artigo
Language:Inglês
Published: The Association for Research in Vision and Ophthalmology 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409074/
https://ncbi.nlm.nih.gov/pubmed/32821517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.9.6.20
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