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Glutamic-Pyruvic Transaminase 1 Facilitates Alternative Fuels for Hepatocellular Carcinoma Growth—A Small Molecule Inhibitor, Berberine

Metabolic reprogramming is an essential hallmark of cancer. Besides the “Warburg effect”, cancer cells also actively reprogram amino acid metabolism to satisfy high nutritional demands in a nutrient-poor environment. In the glucose–alanine cycle, exogenous alanine taken up by hepatocytes is converte...

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Publicat a:Cancers (Basel)
Autors principals: Guo, Wei, Tan, Hor-Yue, Li, Sha, Wang, Ning, Feng, Yibin
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408817/
https://ncbi.nlm.nih.gov/pubmed/32660149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071854
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