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Bone Morphogenetic Protein (BMP)4 But Not BMP2 Disrupts the Barrier Integrity of Retinal Pigment Epithelia and Induces Their Migration: A Potential Role in Neovascular Age-Related Macular Degeneration

Disruption of retinal pigment epithelial (RPE) barrier integrity and RPE migration are hallmark features in neovascular age-related macular degeneration (nAMD), but the underlying causes and pathophysiology are not completely well-defined. Herein, we aimed to evaluate the effect of bone morphogeneti...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Ibrahim, Ahmed S., Hussein, Khaled, Wang, Fang, Wan, Ming, Saad, Nancy, Essa, Maamon, Kim, Ivana, Shakoor, Akbar, Owen, Leah A., DeAngelis, Margaret M., Al-Shabrawey, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408815/
https://ncbi.nlm.nih.gov/pubmed/32707711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9072293
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