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Photochemical and Photobiological Properties of Pyridyl-pyrazol(in)e-Based Ruthenium(II) Complexes with Sub-micromolar Cytotoxicity for Phototherapy

[Image: see text] The discovery of new light-triggered prodrugs based on ruthenium (II) complexes is a promising approach for photoactivated chemotherapy (PACT). The light-mediated activation of “strained” Ru(II) polypyridyl complexes resulted in ligand release and produced a ligand-deficient metal...

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Publicado en:ACS Omega
Main Authors: Havrylyuk, Dmytro, Heidary, David K., Sun, Yang, Parkin, Sean, Glazer, Edith C.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2020
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408248/
https://ncbi.nlm.nih.gov/pubmed/32775891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c02079
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