Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer—Optimization of the Affinity towards PSMA by Linker Modification in Murine Model

Prostate-specific membrane antigen (PSMA) and gastrin-releasing peptide receptor (GRPR) are promising targets for molecular imaging of prostate cancer (PCa) lesions. Due to the heterogenic overexpression of PSMA and GRPR in PCa, a heterodimeric radiotracer with the ability to bind to both targets co...

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Publicat a:Pharmaceutics
Autors principals: Lundmark, Fanny, Abouzayed, Ayman, Mitran, Bogdan, Rinne, Sara S., Varasteh, Zohreh, Larhed, Mats, Tolmachev, Vladimir, Rosenström, Ulrika, Orlova, Anna
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408065/
https://ncbi.nlm.nih.gov/pubmed/32630176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12070614
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