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KLF4 Acts as a wt-CFTR Suppressor through an AKT-Mediated Pathway
Cystic Fibrosis (CF) is caused by >2000 mutations in the CF transmembrane conductance regulator (CFTR) gene, but one mutation—F508del—occurs in ~80% of patients worldwide. Besides its main function as an anion channel, the CFTR protein has been implicated in epithelial differentiation, tissue reg...
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| Izdano u: | Cells |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
MDPI
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7408019/ https://ncbi.nlm.nih.gov/pubmed/32630830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9071607 |
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