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SETD1A Promotes Proliferation of Castration-Resistant Prostate Cancer Cells via FOXM1 Transcription

Androgen deprivation therapy eventually leads to the development of castration-resistant prostate cancer (CRPC). Here, we demonstrate for the first time that the histone H3K4 methyltransferase SETD1A is a major regulator for the proliferation of metastatic CRPC (mCRPC). The expression of SETD1A was...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Yang, Liu, Jin, Mingli, Park, Sung Jean, Seo, Seung-Yong, Jeong, Kwang Won
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407996/
https://ncbi.nlm.nih.gov/pubmed/32629770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071736
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