Probing the DNA Reactivity and the Anticancer Properties of a Novel Tubercidin-Pt(II) Complex

Herein, we reported on the synthesis of a novel Pt(II) neutral complex having as ligand the nucleoside tubercidin, a potent anti-tumor agent extracted from the bacterium Streptomyces Tubercidicus. In detail, the chelation of the metal by a diamine linker installed at C6 purine position of tubercidin...

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Publicado en:Pharmaceutics
Main Authors: D’Errico, Stefano, Falanga, Andrea Patrizia, Capasso, Domenica, Di Gaetano, Sonia, Marzano, Maria, Terracciano, Monica, Roviello, Giovanni Nicola, Piccialli, Gennaro, Oliviero, Giorgia, Borbone, Nicola
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407906/
https://ncbi.nlm.nih.gov/pubmed/32635488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12070627
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