A Mixed-Surface Polyamidoamine Dendrimer for In Vitro and In Vivo Delivery of Large Plasmids

Drug delivery to the brain is highly hindered by the presence of the blood–brain barrier (BBB), which prevents the entry of many potential drugs/biomolecules into the brain. One of the current strategies to achieve gene therapy for neurodegenerative diseases involves direct injection of a viral vect...

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Publicado en:Pharmaceutics
Autores principales: Srinageshwar, Bhairavi, Florendo, Maria, Clark, Brittany, Johnson, Kayla, Munro, Nikolas, Peruzzaro, Sarah, Antcliff, Aaron, Andrews, Melissa, Figacz, Alexander, Swanson, Douglas, Dunbar, Gary L., Sharma, Ajit, Rossignol, Julien
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407876/
https://ncbi.nlm.nih.gov/pubmed/32635142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12070619
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