miR-424 suppresses proliferation and promotes apoptosis of human ovarian granulosa cells by targeting Apelin and APJ expression

Objective: Polycystic ovary syndrome (PCOS) is associated with alteration of Apelin signaling in ovarian granulosa cells (GCs). However, the molecular mechanisms regulating Apelin expression remain poorly understood. This study aims to investigate the role of miR-424 in modulating Apelin expression...

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Bibliographic Details
Published in:Am J Transl Res
Main Authors: Du, Jing, Lin, Xiufeng, Wu, Riran, Gao, Zixuan, Du, Yan, Liao, Yuechan, Quan, Song
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2020
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407740/
https://ncbi.nlm.nih.gov/pubmed/32774725
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