Secoemestrin C inhibits activation of NKT/conventional T cells and protects against concanavalin A-induced autoimmune hepatitis in mice

Secoemestrin C is an epitetrathiodioxopiperazine isolated from Aspergillus nidulans, which has only been reported in terms of inhibiting tumor cell proliferation. Here, we determined the immunomodulatory and hepatoprotective effects of secoemestrin C in a mouse model of acute autoimmune hepatitis. I...

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Publicat a:Am J Transl Res
Autors principals: Tan, Xiaosheng, Sun, Lingjuan, Li, Qin, Qi, Changxing, Fu, Cheng, Zhu, Hucheng, Yang, Xi, Feng, Hao, Li, Yakun, Zhang, Yonghui, Chen, Gang
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2020
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407708/
https://ncbi.nlm.nih.gov/pubmed/32774707
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