Population Pharmacokinetics of Vincristine Related to Infusion Duration and Peripheral Neuropathy in Pediatric Oncology Patients

Vincristine (VCR) is frequently used in pediatric oncology and can be administered intravenously through push injections or 1 h infusions. The effects of administration duration on population pharmacokinetics (PK) are unknown. We described PK differences related to administration duration and the re...

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Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: van de Velde, Mirjam Esther, Panetta, John Carl., Wilhelm, Abraham J., van den Berg, Marleen H., van der Sluis, Inge M., van den Bos, Cor, Abbink, Floor C.H., van den Heuvel-Eibrink, Marry M., Segers, Heidi, Chantrain, Christophe, van der Werff Ten Bosch, Jutte, Willems, Leen, Evans, William E., Kaspers, Gertjan L.
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407622/
https://ncbi.nlm.nih.gov/pubmed/32635465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071789
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