Population Pharmacokinetics of Vincristine Related to Infusion Duration and Peripheral Neuropathy in Pediatric Oncology Patients

Vincristine (VCR) is frequently used in pediatric oncology and can be administered intravenously through push injections or 1 h infusions. The effects of administration duration on population pharmacokinetics (PK) are unknown. We described PK differences related to administration duration and the re...

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Vydáno v:Cancers (Basel)
Hlavní autoři: van de Velde, Mirjam Esther, Panetta, John Carl., Wilhelm, Abraham J., van den Berg, Marleen H., van der Sluis, Inge M., van den Bos, Cor, Abbink, Floor C.H., van den Heuvel-Eibrink, Marry M., Segers, Heidi, Chantrain, Christophe, van der Werff Ten Bosch, Jutte, Willems, Leen, Evans, William E., Kaspers, Gertjan L.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407622/
https://ncbi.nlm.nih.gov/pubmed/32635465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071789
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