Formulation Design, Statistical Optimization, and In Vitro Evaluation of a Naringenin Nanoemulsion to Enhance Apoptotic Activity in A549 Lung Cancer Cells

Naringenin (NAR), a flavonoid mainly found in citrus and grapefruits, has proven anti-cancer activities. However, the poor water solubility and low bioavailability of NAR limits its use as a therapeutic agent. The aim of this study was to develop and optimize stable naringenin nanoemulsions (NAR-NE)...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Md, Shadab, Alhakamy, Nabil A., Aldawsari, Hibah M., Husain, Mohammad, Kotta, Sabna, Abdullah, Samaa T., A. Fahmy, Usama, Alfaleh, Mohamed A., Asfour, Hani Z.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407592/
https://ncbi.nlm.nih.gov/pubmed/32679917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13070152
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