A Forward Genetic Approach to Mapping a P-Element Second Site Mutation Identifies DCP2 as a Novel Tumor Suppressor in Drosophila melanogaster

The use of transposons to create mutations has been the cornerstone of Drosophila genetics in the past few decades. Second-site mutations caused by transpositions are often devoid of transposons and thereby affect subsequent analyses. In a P-element mutagenesis screen, a second site mutation was ide...

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Bibliographische Detailangaben
Veröffentlicht in:G3 (Bethesda)
Hauptverfasser: Mishra, Rakesh, Kunar, Rohit, Mandal, Lolitika, Alone, Debasmita Pankaj, Chandrasekharan, Shanti, Tiwari, Anand Krishna, Tapadia, Madhu Gwaldas, Mukherjee, Ashim, Roy, Jagat Kumar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2020
Schlagworte:
Mutant Screen Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407449/
https://ncbi.nlm.nih.gov/pubmed/32591349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.120.401501
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