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In Vitro and In Vivo Assessment of PEGylated PEI for Anti-IL-8/CxCL-1 siRNA Delivery to the Lungs

Inhalation offers a means of rapid, local delivery of siRNA to treat a range of autoimmune or inflammatory respiratory conditions. This work investigated the potential of a linear 10 kDa Poly(ethylene glycol) (PEG)-modified 25 kDa branched polyethyleneimine (PEI) (PEI-LPEG) to effectively deliver si...

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Detalles Bibliográficos
Publicado en:Nanomaterials (Basel)
Main Authors: Hibbitts, Alan J., Ramsey, Joanne M., Barlow, James, MacLoughlin, Ronan, Cryan, Sally-Ann
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407419/
https://ncbi.nlm.nih.gov/pubmed/32605011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano10071248
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