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Cystic Fibrosis: Overview of the Current Development Trends and Innovative Therapeutic Strategies

Cystic Fibrosis (CF), an autosomal recessive genetic disease, is caused by a mutation in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). This mutation reduces the release of chloride ions (Cl(−)) in epithelial tissues, and hyperactivates the epithelial sodium channe...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Almughem, Fahad A., Aldossary, Ahmad M., Tawfik, Essam A., Alomary, Mohammad N., Alharbi, Waleed S., Alshahrani, Mohammad Y., Alshehri, Abdullah A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407299/
https://ncbi.nlm.nih.gov/pubmed/32630625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12070616
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