VariantSpark: Cloud-based machine learning for association study of complex phenotype and large-scale genomic data

BACKGROUND: Many traits and diseases are thought to be driven by >1 gene (polygenic). Polygenic risk scores (PRS) hence expand on genome-wide association studies by taking multiple genes into account when risk models are built. However, PRS only considers the additive effect of individual genes b...

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Bibliografische gegevens
Gepubliceerd in:Gigascience
Hoofdauteurs: Bayat, Arash, Szul, Piotr, O’Brien, Aidan R, Dunne, Robert, Hosking, Brendan, Jain, Yatish, Hosking, Cameron, Luo, Oscar J, Twine, Natalie, Bauer, Denis C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
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Technical Note
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407261/
https://ncbi.nlm.nih.gov/pubmed/32761098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giaa077
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