Computer-Aided Design, Synthesis, and Antiviral Evaluation of Novel Acrylamides as Potential Inhibitors of E3-E2-E1 Glycoproteins Complex from Chikungunya Virus

Chikungunya virus (CHIKV) causes an infectious disease characterized by inflammation and pain of the musculoskeletal tissues accompanied by swelling in the joints and cartilage damage. Currently, there are no licensed vaccines or chemotherapeutic agents to prevent or treat CHIKV infections. In this...

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Publicado no:Pharmaceuticals (Basel)
Main Authors: Passos, Gabriel Felipe Silva, Gomes, Matheus Gabriel Moura, de Aquino, Thiago Mendonça, de Araújo-Júnior, João Xavier, de Souza, Stephannie Janaina Maia, Cavalcante, João Pedro Monteiro, dos Santos, Elane Conceição, Bassi, Ênio José, da Silva-Júnior, Edeildo Ferreira
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407227/
https://ncbi.nlm.nih.gov/pubmed/32629969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13070141
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