Human Cytomegalovirus miR-US5-2 Downregulation of GAB1 Regulates Cellular Proliferation and UL138 Expression through Modulation of Epidermal Growth Factor Receptor Signaling Pathways

Regulation of epidermal growth factor (EGF) receptor (EGFR) signaling is critical for the replication of human cytomegalovirus (HCMV) as well as latency and reactivation in CD34(+) hematopoietic progenitor cells. HCMV microRNAs (miRNAs) provide a means to modulate the signaling activated by EGF thro...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Hancock, Meaghan H., Mitchell, Jennifer, Goodrum, Felicia D., Nelson, Jay A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407068/
https://ncbi.nlm.nih.gov/pubmed/32759334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00582-20
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