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BECN1 promotes radiation-induced G2/M arrest through regulation CDK1 activity: a potential role for autophagy in G2/M checkpoint

Authophagy and G2/M arrest are two important mechanistic responses of cells to ionizing radiation (IR), in particular the IR-induced fibrosis. However, what interplayer and how it links the autophagy and the G(2)/M arrest remains elusive. Here, we demonstrate that the autophagy-related protein BECN1...

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Dades bibliogràfiques
Publicat a:Cell Death Discov
Autors principals: Huang, Ruixue, Gao, Shanshan, Han, Yanqin, Ning, Huacheng, Zhou, Yao, Guan, Hua, Liu, Xiaodan, Yan, Shuang, Zhou, Ping-Kun
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406511/
https://ncbi.nlm.nih.gov/pubmed/32802407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-020-00301-2
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