Life span extension by glucose restriction is abrogated by methionine supplementation: Cross-talk between glucose and methionine and implication of methionine as a key regulator of life span

Caloric restriction (CR) is known to extend life span across species; however, the molecular mechanisms are not well understood. We investigate the mechanism by which glucose restriction (GR) extends yeast replicative life span, by combining ribosome profiling and RNA-seq with microfluidic-based sin...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Zou, Ke, Rouskin, Silvia, Dervishi, Kevin, McCormick, Mark A., Sasikumar, Arjun, Deng, Changhui, Chen, Zhibing, Kaeberlein, Matt, Brem, Rachel B., Polymenis, Michael, Kennedy, Brian K., Weissman, Jonathan S., Zheng, Jiashun, Ouyang, Qi, Li, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406366/
https://ncbi.nlm.nih.gov/pubmed/32821821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba1306
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