Stromal β-catenin activation impacts nephron progenitor differentiation in the developing kidney and may contribute to Wilms tumor

Wilms’ tumor (WT) morphologically resembles the embryonic kidney, consisting of blastema, epithelial and stromal components, suggesting tumors arise from the dysregulation of normal development. β-Catenin activation is observed in a significant proportion of WTs; however, much remains to be understo...

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Foilsithe in:Development
Main Authors: Drake, Keri A., Chaney, Christopher P., Das, Amrita, Roy, Priti, Kwartler, Callie S., Rakheja, Dinesh, Carroll, Thomas J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Company of Biologists Ltd 2020
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406317/
https://ncbi.nlm.nih.gov/pubmed/32541007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.189597
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