Deletion of the Mitochondrial Matrix Protein CyclophilinD Prevents Parvalbumin Interneuron Dysfunctionand Cognitive Deficits in a Mouse Model of NMDA Hypofunction

Redox dysregulation and oxidative stress are final common pathways in the pathophysiology of a variety of psychiatric disorders, including schizophrenia. Oxidative stress causes dysfunction of GABAergic parvalbumin (PV)-positive interneurons (PVI), which are crucial for the coordination of neuronal...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Phensy, Aarron, Lindquist, Kathy L., Lindquist, Karen A., Bairuty, Dania, Gauba, Esha, Guo, Lan, Tian, Jing, Du, Heng, Kroener, Sven
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406283/
https://ncbi.nlm.nih.gov/pubmed/32605939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0880-20.2020
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