Single cell RNA sequencing identifies an early monocyte gene signature in acute respiratory distress syndrome

Acute respiratory distress syndrome (ARDS) results from overwhelming pulmonary inflammation. Prior bulk RNA sequencing provided limited insights into ARDS pathogenesis. We used single cell RNA sequencing to probe ARDS at a higher resolution. PBMCs of patients with pneumonia and sepsis with early ARD...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Jiang, Yale, Rosborough, Brian R., Chen, Jie, Das, Sudipta, Kitsios, Georgios D., McVerry, Bryan J., Mallampalli, Rama K., Lee, Janet S., Ray, Anuradha, Chen, Wei, Ray, Prabir
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406263/
https://ncbi.nlm.nih.gov/pubmed/32554932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.135678
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