PD-1 does not mark tumor-infiltrating CD8+ T cell dysfunction in human gastric cancer

BACKGROUND: Overexpression of programmed cell death protein 1 (PD-1) is linked to CD8+ T cell dysfunction and contributes to tumor immune escape. However, the prevalence and functional regulations of PD-1 expression on CD8+ T cells in human gastric cancer (GC) remain largely unknown. METHODS: Flow c...

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Detalles Bibliográficos
Publicado en:J Immunother Cancer
Main Authors: Shen, Yang, Teng, Yongsheng, Lv, Yipin, Zhao, Yongliang, Qiu, Yuan, Chen, Weisan, Wang, Lina, Wang, Ying, Mao, Fangyuan, Cheng, Ping, Ma, Daiyuan, Zhuang, Yuan, Zou, Quanming, Peng, Liusheng
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2020
Assuntos:
Basic Tumor Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406116/
https://ncbi.nlm.nih.gov/pubmed/32753468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2019-000422
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