Mkrn2 deficiency induces teratozoospermia and male infertility through p53/PERP-mediated apoptosis in testis

The apoptosis that occurs in the immature testis under physiological conditions is necessary for male germ cell development, whereas improper activation of apoptosis can impair spermatogenesis and cause defects in reproduction. We previously demonstrated that in mice, the makorin-2 (Mkrn2) gene is e...

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Bibliographic Details
Published in:Asian J Androl
Main Authors: Qian, Ying-Chen, Xie, Yun-Xia, Wang, Chao-Shan, Shi, Zhu-Mei, Jiang, Cheng-Fei, Tang, Yun-Yi, Qian, Xu, Wang, Lin, Jiang, Bing-Hua
Format: Artigo
Language:Inglês
Published: Wolters Kluwer - Medknow 2019
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406093/
https://ncbi.nlm.nih.gov/pubmed/31489847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/aja.aja_76_19
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